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WORLD / Health
Device to detect bird flu virus created
(Agencies)
Updated: 2007-09-24 11:09
HONG KONG -- Researchers in Singapore have created a handheld device that
can detect the H5N1 bird flu virus from throat swab samples in under 30
minutes, raising hopes it will lead to rapid detection and containment of
the virus.
A worker injects a duckling with the bird flu vaccine at a duck farm
following an outbreak of bird flu, in Panyu district of Guangzhou, South
China's Guangdong Province, September 18, 2007. [Reuters]
Conventional laboratory tests take around 4 hours, and require machines
to first isolate and amplify the virus before it is tested.
Writing in the latest issue of Nature Medicine, the scientists said the
new device would allow decentralized testing of the H5N1 virus,
especially in countries that lack basic public health resources.
H5N1, a disease found mostly in birds, is endemic in many parts of Asia
and experts have warned for years that it could spark a pandemic, killing
millions of people, if it learns to jump from person to person.
"The World Health Organisation containment plan aims to stop an epidemic
locally in order to prevent a global disaster," the scientists said.
"In the event of a flu epidemic, its rapid containment would depend on
the prompt identification of the first cases. But as routine surveillance
may be problematic in countries with limited public health resources,
low-cost, easy-to-use detection (procedures) would be advantageous."
The all-in-one device is able to isolate, purify and amplify the viral
DNA from raw throat swab samples and put it through an H5N1 detection
test.
"The answers you will get is: am I infected? If yes, how 'severe' is it?"
one of the researchers, Juergen Pipper of Singapore's Institute of
Bioengineering and Nanotechnology, wrote in an email to Reuters.
The team ran several hundred tests on the device.
"The accuracy is comparable to conventional equipment, although we are
faster and cheaper," Pipper said.
The scientists hope to use the device to test for other viruses, such as
SARS, AIDS and hepatitis B.
"In addition, it may be applicable not only to the flu virus, but could
be adapted to other infectious agents, and to other bodily fluids like
blood, urine or saliva," they said.
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